Índice completo de variantes genéticas

Fast-twitch muscle fiber protein. R577X sprint gene.

Converts pyridoxal phosphate to pyridoxal for cellular uptake.

Essential partner of cubilin for B12 absorption.

Metabolizes pyridoxal to 4-pyridoxic acid.

Secondary pathway for carotenoid cleavage.

Supports neuron survival and growth. Val66Met affects memory.

Oxidizes choline to betaine aldehyde.

Tendon and ligament injury risk.

Receptor for intrinsic factor-B12 complex in ileum.

Inactivates vitamin D metabolites. Regulates vitamin D levels.

Kidney enzyme converting 25OHD to active 1,25OH2D.

Metabolizes vitamin E and vitamin K.

Reduces dihydrofolate to tetrahydrofolate. Crucial for folate cycle.

Converts T4 to active T3 in tissues.

Intestinal enzyme for dietary folate absorption.

Vitamin K-dependent carboxylation of clotting factors.

Intrinsic factor production for B12 absorption.

Esterifies retinol for storage in liver.

Intracellular processing of B12.

Enzima clave en el metabolismo del folato y el ciclo de metilacion

Mantiene la enzima MTR en estado activo

Associated with vitamin D levels.

Phosphorylates vitamin B6 vitamers to active forms.

Sintetiza fosfatidilcolina de novo; importante para la salud hepática y el desarrollo de membranas fetales

Sleep timing

Converts pyridoxine/pyridoxamine to active pyridoxal-5-phosphate.

Major transport protein for retinol in blood.

Interconverts serine and glycine with THF. Key for one-carbon metabolism.

Reduced folate carrier for cellular folate uptake.

Transportador intestinal de vitamina C

SVCT2 - vitamin C transporter in various tissues.

Cellular receptor for retinol uptake from RBP4.

Haptocorrin - binds B12 in saliva and stomach.

Liver protein regulating alpha-tocopherol blood levels.

Essential for DNA synthesis. Target of folate-related metabolism.

Receptor nuclear que media los efectos de la vitamina D

Recycles vitamin K for clotting factor activation.

Intestinal copper absorption and transport.

Copper excretion in liver. Wilson disease gene.

Convierte el beta-caroteno en vitamina A

Receptor sensor de calcio en sangre; regula la secreción de parathormona y la homeostasis del calcio

Magnesium transport in kidney.

Copper transport protein and ferroxidase.

Enzyme that activates vitamin D in the liver

Provides precursor for vitamin D synthesis in skin.

Selenium-dependent thyroid hormone activation.

Iron storage with ferroxidase activity.

Iron storage protein component.

Influye en la absorcion de B12 en el intestino

Principal proteina transportadora de vitamina D en sangre

Reduce hidroperóxidos con glutatión; protección contra el daño oxidativo mediante selenio

Lipid-specific selenoprotein antioxidant.

Master regulator of iron absorption.

Zinc binding and homeostasis protein.

Major metallothionein for zinc homeostasis.

Regenera metionina a partir de homocisteina utilizando vitamina B12

Major selenium transport protein in blood.

Intestinal iron absorption transporter.

Major intestinal zinc absorption transporter.

Exports iron from cells to blood.

Active iodide transport into thyroid.

Iron uptake in liver. Regulates hepcidin.

Precursor for thyroid hormone synthesis.

Thyroid hormone synthesis enzyme.

Primary intestinal magnesium absorption channel.

Ubiquitous magnesium channel.

Epithelial calcium channel for absorption.

Intestinal calcium absorption channel.

Fructose metabolism enzyme. Hereditary fructose intolerance.

Diamine oxidase - degrades histamine in gut.

Convierte homocisteína en cistationina; primer paso de la vía de transulfuración

Immune regulation gene linked to celiac disease.

Regula la absorcion de hierro en el intestino

Inactiva la histamina mediante N-metilación intracelular; complementaria de la DAO extracelular

Enzyme that digests lactose (milk sugar)

Regula la expresion del gen de la lactasa (tolerancia a la lactosa)

Fructose transporter in intestine.

Transporta zinc a los granulos secretores de las celulas beta pancreaticas

Oxidizes sulfite to sulfate. Essential detoxification.

Main iron transport protein in blood.

Regulates hepcidin. Matriptase-2.

P-glycoprotein efflux pump. Drug transport.

Converts hydrogen peroxide to water.

Metabolizes polycyclic aromatic hydrocarbons.

Drug metabolism. Proton pump inhibitors.

Major drug metabolizing enzyme. Warfarin metabolism.

Metabolizes 25 percent of all drugs. Highly polymorphic.

Metabolizes 50 percent of all drugs. Major CYP enzyme.

Additional drug metabolism pathway.

Principal enzima para la degradación de histamina en el intestino; influye en la intolerancia a la histamina y las reacc...

Detoxification enzyme important for antioxidant defense

Detoxification enzyme important for toxin elimination

Celiac disease risk

Celiac disease risk

HLA-DQ2 DQ8 component for celiac disease risk.

HLA-DQ2 DQ8 component for celiac disease risk.

Acetylation of drugs and carcinogens.

Desintoxica quinonas y protege contra el estres oxidativo

Cilantro taste

Cytoplasmic antioxidant enzyme.

Neutraliza radicales superóxido en las mitocondrias; protección contra el estrés oxidativo

Sulfation of phenols and estrogens.

Bitter taste perception

Bilirubin conjugation. Gilbert syndrome.

HDL component

Triglyceride metabolism

Principal regulador del ritmo circadiano; influye en el ciclo sueño-vigilia, el metabolismo y la secreción hormonal

Degrada catecolaminas (dopamina, adrenalina, noradrenalina); influye en el estado de ánimo, la cognición y la respuesta ...

Dopamine reuptake. ADHD medication target.

Linked to novelty seeking and ADHD.

Metabolismo de acidos grasos omega-3 y omega-6

Enzyme involved in omega fatty acid metabolism

GABA receptor affecting anxiety and alcohol response.

Synthesizes GABA from glutamate.

Major serotonin receptor. Affects mood and appetite.

Insulin signaling cascade.

HDL metabolism

Degrades serotonin dopamine norepinephrine. Warrior gene.

Primarily degrades dopamine and phenylethylamine.

Core circadian rhythm gene.

Antioxidant enzyme

Regulador principal de la diferenciacion de celulas adiposas y la sensibilidad a la insulina

Serotonin reuptake. SSRI target. Short Long alleles.

Principal factor de riesgo genetico para la diabetes tipo 2

Rate-limiting enzyme in dopamine synthesis.

Peripheral serotonin synthesis.

Brain serotonin synthesis.

Leukotriene synthesis. Inflammation pathway.

Estrogen metabolism. Affects detox capacity.

Enzima de detoxificacion de fase II que conjuga glutation a toxinas

Th1 cytokine. Immune activation.

Anti-inflammatory cytokine.

Major pro-inflammatory cytokine.

Th2 cytokine. Allergies and atopy.

Enzima de fase II que metaboliza aminas aromaticas e isoniazida

Master inflammatory transcription factor.

Principal citocina proinflamatoria; regula la inflamación sistémica y la defensa inmune

Sulfonylurea receptor. Insulin secretion.

Salivary amylase. Starch digestion. Copy number varies.

Inflammatory marker. Cardiovascular risk.

Glucose sensor in pancreas and liver. MODY2.

Transcription factor for insulin secretion. MODY3.

Glucose metabolism regulator. MODY1.

Regula la inflamación aguda y las respuestas inmunes; influye en la regeneración muscular y la sensibilidad a la insulin...

Insulin signaling in liver and beta cells.

Pancreatic beta cell potassium channel.

Master regulator of mitochondrial biogenesis.

Glucose transporter in liver and pancreas.

Insulin-responsive glucose transporter.

Primer paso del metabolismo del alcohol

Additional alcohol dehydrogenase isoform.

Stomach alcohol metabolism.

Caffeine blocks this receptor. Affects sensitivity.

Induces CYP1A2 expression.

Convierte el acetaldehido en acetato

Principal enzima para el metabolismo de la cafeina

Alternative alcohol metabolism pathway.

Brown fat thermogenesis receptor.

Hunger hormone.

Satiety hormone from fat tissue.

Potent appetite stimulant.

Precursor for satiety signals alpha-MSH.

Strongly associated with BMI.

Brown fat thermogenesis protein.

Energy expenditure regulation.

Muscle energy expenditure.

Reverse cholesterol transport. HDL formation.

Convierte angiotensina I en II; regula la presion arterial

Salt-sensitive blood pressure gene.

Insulin sensitivity and fat metabolism hormone.

Receptor involved in bronchodilation and fat metabolism

Precursor in blood pressure regulation.

Inhibits LPL. Regulates triglycerides.

Inhibits LPL in fasting state.

Main protein of HDL. Cardioprotective.

Main protein of LDL. Familial hypercholesterolemia gene.

Inhibits lipoprotein lipase. Affects triglycerides.

Metabolismo de lipidos y salud cardiovascular

Major dopamine receptor. Affects reward sensitivity.

Sintetiza ácidos grasos omega-3 de cadena muy larga (EPA a DHA); marcador de metilación del ADN para el envejecimiento b...

Involucrado en la síntesis de ácidos grasos de cadena larga a partir de precursores C18 y C20; influye en el equilibrio ...

Influye en la regulacion del apetito y el almacenamiento de grasa

Rate-limiting enzyme in cholesterol synthesis. Statin target.

Clears LDL from blood. Familial hypercholesterolemia.

Hypothalamic leptin signaling.

Breaks down triglycerides in lipoproteins.

Central appetite regulation. Satiety signaling.

Produces NO for vasodilation.

Intestinal cholesterol absorption. Ezetimibe target.

Regula la degradacion del receptor LDL y los niveles de LDL-colesterol

I D polymorphism affects endurance vs power.

Energy metabolism during exercise.

Transfiere esteres de colesterol entre particulas HDL y LDL

Bone and tendon structure. Injury risk.

Red blood cell production for oxygen capacity.

Joint and cartilage development. Injury risk.

Response to low oxygen. Altitude adaptation.

Lactate transport during exercise.

Muscle growth inhibitor. Less equals more muscle.

Vasodilation and blood flow during exercise.

Fat oxidation during exercise.

Endurance training adaptation. Mitochondrial biogenesis.

Angiogenesis for endurance adaptation.

Convierte homocisteína en metionina; vía alternativa de metilación independiente de B12

Main transport protein for B12 delivery to tissues.