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GPX1
Glutathione Peroxidase 1
Vitamins & Minerals Chr. 3 1 SNP analyzed 1 food interactions

About this gene

Selenium-dependent antioxidant enzyme.

Analyzed variants (SNPs)

rs1050450 GPX1 Pro198Leu Population frequency: 32.0% Chr. 3 : 49,394,835
Genotype Impact What it means
CC (Normal) Normal Normal GPX1 activity - good selenium-dependent antioxidant defence. Maintain adequate selenium (1-2 Brazil nuts/day).
CT (Carrier) Low impact Reduced GPX1 activity - modestly weaker antioxidant protection. Ensure optimal selenium (Brazil nuts, fish, eggs) and antioxidant-rich foods.
TT (Variant) Moderate Significantly reduced GPX1 activity - higher oxidative stress. Prioritise selenium, zinc and colourful antioxidants; avoid smoking and excess alcohol.

Foods & nutrition for GPX1

Beneficial foods

Beneficial foods
Brazil Nuts
Highest natural selenium source for selenoprotein production

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