Language
Induces CYP1A2 expression.
| Genotype | Impact | What it means |
|---|---|---|
| CC (Normal) | Normal | Higher CYP1A2 induction - faster caffeine metabolism. You generally tolerate coffee well; keep it before mid-afternoon. |
| CT (Carrier) | Low impact | Intermediate CYP1A2 induction - average caffeine clearance. Watch afternoon coffee if it affects your sleep. |
| TT (Variant) | Moderate | Lower CYP1A2 induction - slower caffeine processing. Limit caffeine to the morning; green tea (with L-theanine) is a gentler option. |
| Genotype | Impact | What it means |
|---|---|---|
| GG (Normal) | Normal | Normal CYP1A2 induction - standard caffeine and xenobiotic processing. |
| GA (Carrier) | Low impact | Reduced enzyme induction - slower response to dietary/environmental inducers; caffeine may clear a bit more slowly. Keep caffeine moderate. |
| AA (Variant) | Moderate | Lower CYP1A2 expression and slower caffeine metabolism. Favour morning-only caffeine and watch your individual response. |
Upload your 23andMe or AncestryDNA file and get a personalized nutrition plan based on your exact genotype.
Get My DNA Report →