TCF7L2 Gene (Transcription Factor 7-Like 2) | FuelYourDNA

About this gene

Gene strongly associated with type 2 diabetes risk

Regulates insulin secretion and glucose homeostasis

rs7903146 TCF7L2 rs7903146 Population frequency: 30.0% Chr. 10 : 114,758,349

TCF7L2 variant associated with type 2 diabetes risk

Genotype	Impact	What it means
CC (Normal)	Normal	Normal insulin signaling. Lower genetic risk for type 2 diabetes.
CT (Carrier)	Moderate	Moderately increased diabetes risk. Focus on low glycemic foods and regular exercise.
TT (Variant)	High impact	Higher diabetes risk. Prioritize low glycemic diet, regular exercise, and maintain healthy weight.

rs12255372 TCF7L2 rs12255372 Population frequency: 27.0% Chr. 10 : 114,808,902

Genotype	Impact	What it means
GG (Normal)	Normal	Normal insulin signaling. Lower genetic risk for type 2 diabetes.
GT (Carrier)	Low impact	Moderately increased diabetes risk. Focus on low glycemic foods and regular exercise.
TT (Variant)	Moderate	Higher diabetes risk. Prioritize low glycemic diet, regular exercise, and maintain healthy weight.