Reduced folate carrier for cellular folate uptake.
| Genotype | Impact | What it means |
|---|---|---|
| GG (Normal) | Normal | Normal cellular folate transport - folate enters cells efficiently. Maintain folate-rich foods (leafy greens, legumes). |
| GA (Carrier) | Low impact | Reduced cellular folate uptake - slightly lower folate inside cells. Increase natural folate and consider methylfolate if combined with MTHFR variants. |
| AA (Variant) | Moderate | Significantly reduced folate transport - lower intracellular folate. Prioritise leafy greens and legumes; methylfolate may help, especially alongside MTHFR variants. |
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