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SLC19A1
Folate Transporter
Methylation Cycle Chr. 21 1 SNP analyzed

About this gene

Reduced folate carrier for cellular folate uptake.

Analyzed variants (SNPs)

rs1051266 RFC1 80G-A Population frequency: 48.0% Chr. 21 : 46,934,667
Genotype Impact What it means
GG (Normal) Normal Normal cellular folate transport - folate enters cells efficiently. Maintain folate-rich foods (leafy greens, legumes).
GA (Carrier) Low impact Reduced cellular folate uptake - slightly lower folate inside cells. Increase natural folate and consider methylfolate if combined with MTHFR variants.
AA (Variant) Moderate Significantly reduced folate transport - lower intracellular folate. Prioritise leafy greens and legumes; methylfolate may help, especially alongside MTHFR variants.

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