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Metabolizes polycyclic aromatic hydrocarbons.
| Genotype | Impact | What it means |
|---|---|---|
| AA (Normal) | Normal | Normal CYP1A1 activity - standard handling of polycyclic aromatic hydrocarbons (from smoke, char-grilled food). Keep cruciferous veg in your diet. |
| AG (Carrier) | Low impact | Increased CYP1A1 activity - faster conversion of PAHs into reactive metabolites. Limit charred/smoked foods and eat cruciferous vegetables (broccoli, sprouts) regularly. |
| GG (Variant) | Moderate | High CYP1A1 activity - more reactive metabolites from smoke and charred food. Avoid burnt/char-grilled meat and smoking; prioritise cruciferous vegetables and antioxidants. |
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