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KCNJ11
Potassium Channel KCNJ11
Cardiovascular Health Chr. 11 1 SNP analyzed

About this gene

Pancreatic beta cell potassium channel.

Analyzed variants (SNPs)

rs5219 KCNJ11 E23K Population frequency: 35.0% Chr. 11 : 17,409,572
Genotype Impact What it means
CC (Normal) Normal Normal insulin secretion
CT (Carrier) Low impact Slightly impaired enzymatic activity, supports remain adequate with a varied diet.
TT (Variant) Moderate KK genotype, reduced pancreatic beta-cell insulin secretion via altered K_ATP channel function. Diabetes risk allele; favour low-glycaemic carbohydrates and regular physical activity to support insulin sensitivity.

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