Pancreatic beta cell potassium channel.
| Genotype | Impact | What it means |
|---|---|---|
| CC (Normal) | Normal | Normal insulin secretion |
| CT (Carrier) | Low impact | Slightly impaired enzymatic activity, supports remain adequate with a varied diet. |
| TT (Variant) | Moderate | KK genotype, reduced pancreatic beta-cell insulin secretion via altered K_ATP channel function. Diabetes risk allele; favour low-glycaemic carbohydrates and regular physical activity to support insulin sensitivity. |
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