Cardiovascular Health

AGT Angiotensinogen

Precursor in blood pressure regulation.

Chromosome
1
Variants read
1
Foods
0
Fig. 1Position of AGT on chromosome 1 approximate, banding stylised
AGT · rs699
0 Mb · p armcentromereq arm · 249 Mb
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Analyzed variants (SNPs)

How to read this: each row is one possible genotype, the two DNA letters you carry at this position, one inherited from each parent. "Normal" matches the more common version; "Carrier" (heterozygous) means you have one copy of each version, usually a partial effect; "Variant" (homozygous) means both copies carry the less common version, usually the strongest effect. The estimated frequency below is calculated from the variant's frequency in the general population (Hardy-Weinberg principle) — it is a population estimate, not a measurement of our own customers.

rs699 AGT M235T Population frequency: 42.0% Chr. 1 : 230,710,048
Genotype Impact Est. frequency What it means
CCNormal Normal ~34% Lower angiotensinogen levels; blood pressure is not very sensitive to salt.
CTCarrier Low impact ~49% Intermediate angiotensinogen levels.
TTVariant Moderate ~18% Higher angiotensinogen levels; blood pressure is more salt-sensitive. Keep everyday sodium moderate and reserve salty drinks for long, sweaty sessions.

Estimated with the Hardy-Weinberg principle from the variant's population frequency, not measured directly.

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