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Uses betaine to remethylate homocysteine.
| Genotype | Impact | What it means |
|---|---|---|
| GG (Normal) | Normal | Normal betaine-homocysteine metabolism. Maintain choline-rich foods (eggs, fish). |
| GA (Carrier) | Low impact | Slightly altered betaine pathway - choline-rich foods support homocysteine clearance. Eggs, fish and cruciferous vegetables are beneficial. |
| AA (Variant) | Moderate | Altered betaine metabolism. Prioritise choline (eggs, liver) and consider betaine (TMG); monitor homocysteine alongside folate and B12 status. |
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