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NQO1
NAD-P-H Quinone Dehydrogenase 1
Detox & Drug Metabolism Chr. 16 1 SNP analyzed 1 food interactions

About this gene

Quinone detoxification. Vitamin K metabolism.

Analyzed variants (SNPs)

rs1800566 NQO1-2 Pro187Ser Population frequency: 22.0% Chr. 16 : 69,711,242
Genotype Impact What it means
CC (Normal) Normal Normal NQO1 activity - efficient detox of quinones and recycling of antioxidants (CoQ10, vitamin E). Keep a colourful, plant-rich diet.
CT (Carrier) Moderate Moderately reduced NQO1 activity - weaker quinone detox and antioxidant recycling. Boost sulforaphane (broccoli, sprouts) and antioxidant-rich foods.
TT (Variant) High impact Low/absent NQO1 activity - impaired detox and higher oxidative/carcinogen sensitivity. Prioritise cruciferous vegetables and colourful antioxidants; avoid smoking.

Foods & nutrition for NQO1

Beneficial foods

Beneficial foods
Broccoli
Sulforaphane activates detox enzymes

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