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Insulin signaling cascade.
| Genotype | Impact | What it means |
|---|---|---|
| CC (Normal) | Normal | Normal insulin signaling |
| CT (Carrier) | Low impact | Reduced IRS1 insulin signalling, tendency toward mild insulin resistance. Lower glycaemic load, regular physical activity, and magnesium-rich foods improve insulin sensitivity. |
| TT (Variant) | Moderate | TT genotype, increased insulin resistance risk. Regular exercise is highly beneficial. Prioritise low-glycaemic carbohydrates, fibre, and adequate protein at each meal. |
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