Home / Gene Variants / ADORA2A
ADORA2A
Adenosine A2A Receptor
Caffeine Metabolism Chr. 22 1 SNP analyzed

About this gene

Caffeine blocks this receptor. Affects sensitivity.

Analyzed variants (SNPs)

rs5751876 ADORA2A 1976T-C Population frequency: 45.0% Chr. 22 : 24,825,166
Genotype Impact What it means
TT (Normal) Normal Normal caffeine sensitivity
TC (Carrier) Low impact Increased anxiety response to caffeine. Consider reducing intake or switching to green tea (L-theanine buffers caffeine effect).
CC (Variant) Moderate High caffeine sensitivity, slow caffeine clearance can cause anxiety, jitters and insomnia. Limit caffeine to morning hours and consider <100 mg/day.

Discover your ADORA2A variant

Upload your 23andMe or AncestryDNA file and get a personalized nutrition plan based on your exact genotype.

Get My DNA Report →