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Regulates hepcidin. Matriptase-2.
| Genotype | Impact | What it means |
|---|---|---|
| AA (Normal) | Normal | Normal hepcidin regulation |
| AG (Carrier) | Low impact | Mildly elevated hepcidin, slightly reduced iron absorption. Maintain a varied iron-rich diet and pair plant iron with vitamin C. |
| GG (Variant) | Moderate | Elevated hepcidin levels reduce intestinal iron absorption, increasing anaemia risk. Ensure adequate iron intake (red meat, shellfish, legumes), pair with vitamin C, and monitor ferritin periodically. |
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