Central appetite regulation. Satiety signaling.
| Genotype | Impact | What it means |
|---|---|---|
| TT (Normal) | Normal | Normal satiety signaling |
| TC (Carrier) | Low impact | Reduced satiety signalling, fullness cues may be weaker. Prioritise protein and fibre at each meal, eat slowly, and maintain regular meal timing. |
| CC (Variant) | Moderate | C/C genotype, impaired satiety signalling at the melanocortin-4 receptor. Higher dietary fiber (30–40 g/day), generous protein at each meal, and structured meal timing significantly improve fullness perception. |
Upload your 23andMe or AncestryDNA file and get a personalized nutrition plan based on your exact genotype.
Get My DNA Report →