Home / Gene Variants / PPARGC1A
PPARGC1A
PGC-1 Alpha
Cardiovascular Health Chr. 4 1 SNP analyzed

About this gene

Master regulator of mitochondrial biogenesis.

Analyzed variants (SNPs)

rs8192678 PPARGC1A Gly482Ser Population frequency: 35.0% Chr. 4 : 23,814,039
Genotype Impact What it means
GG (Normal) Normal Normal mitochondrial biogenesis - good response to endurance training. Stay active and support mitochondria (omega-3s, CoQ10-rich foods).
GA (Carrier) Low impact Intermediate mitochondrial function. Regular aerobic exercise and a nutrient-dense diet support energy metabolism.
AA (Variant) Moderate Reduced mitochondrial biogenesis and a higher type-2-diabetes signal. Prioritise regular aerobic plus interval training, a lower-glycaemic diet and magnesium-rich foods.

Discover your PPARGC1A variant

Upload your 23andMe or AncestryDNA file and get a personalized nutrition plan based on your exact genotype.

Get My DNA Report →