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Major dopamine receptor. Affects reward sensitivity.
| Genotype | Impact | What it means |
|---|---|---|
| GG (Normal) | Normal | Normal vitamin D receptor function and calcium absorption. |
| GA (Carrier) | Low impact | A1 allele carrier, moderately reduced D2 dopamine receptor density. Linked to reward-driven eating and obesity susceptibility. Behavioural strategies (mindful eating, reduced exposure to ultra-processed foods) are beneficial. |
| AA (Variant) | Moderate | Reduced vitamin D receptor sensitivity. Higher vitamin D intake recommended (2000-4000 IU/day). |
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