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Kidney enzyme converting 25OHD to active 1,25OH2D.
| Genotype | Impact | What it means |
|---|---|---|
| GG (Normal) | Normal | Normal activation of vitamin D to its active form (calcitriol). Maintain adequate vitamin D from sun, oily fish or supplements. |
| GT (Carrier) | Low impact | Slightly reduced vitamin D activation. Ensure good vitamin D status (sun, oily fish, D3 supplement) and adequate magnesium, which the conversion needs. |
| TT (Variant) | Moderate | Reduced conversion to active 1,25(OH)2D. Aim for the higher end of optimal vitamin D, ensure magnesium intake, and retest levels periodically. |
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