Weight Management

ADRB3 Beta-3 Adrenergic Receptor

Brown fat thermogenesis receptor.

Chromosome
8
Variants read
1
Foods
0
Fig. 1Position of ADRB3 on chromosome 8 approximate, banding stylised
ADRB3 · rs4994
0 Mb · p armcentromereq arm · 146 Mb
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Analyzed variants (SNPs)

How to read this: each row is one possible genotype, the two DNA letters you carry at this position, one inherited from each parent. "Normal" matches the more common version; "Carrier" (heterozygous) means you have one copy of each version, usually a partial effect; "Variant" (homozygous) means both copies carry the less common version, usually the strongest effect. The estimated frequency below is calculated from the variant's frequency in the general population (Hardy-Weinberg principle) — it is a population estimate, not a measurement of our own customers.

rs4994 ADRB3 Trp64Arg Population frequency: 10.0% Chr. 8 : 37,823,798
Genotype Impact Est. frequency What it means
TTNormal Normal ~81% Trp/Trp: normal resting metabolic rate and thermogenesis.
TCCarrier Low impact ~18% Trp/Arg: slightly lower resting metabolic rate.
CCVariant Moderate ~1% Arg/Arg: lower resting metabolic rate and a tendency to store fat; regular training and a higher protein intake offset it.

Estimated with the Hardy-Weinberg principle from the variant's population frequency, not measured directly.

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