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Regula a expressao do gene da lactase (tolerancia a lactose)
Contem elemento regulatorio que controla a expressao do gene LCT
Determina a persistencia da lactase em adultos
| Genótipo | Impacto | O que significa |
|---|---|---|
| GG (Normal) | Impacto alto | Lactose intolerant, lactase non-persistence (ancestral GG genotype). Consider lactose-free alternatives or lactase supplements. |
| GA (Portador) | Impacto baixo | Lactase persistent (one persistence allele) - your genes let you keep digesting lactose into adulthood, so genetic (primary) lactose intolerance is unlikely. Important: a DNA test only detects the genetic form. It cannot rule out acquired (secondary) lactose intolerance from age, gut issues or illness, which can affect anyone. |
| AA (Variante) | Normal | Lactase persistent (both persistence alleles) - you are genetically well-equipped to digest lactose into adulthood. Important: this is a genetic result only. Acquired (secondary) lactose intolerance from age, gut issues or illness is not detectable by DNA and can still occur. |
| Genótipo | Impacto | O que significa |
|---|---|---|
| CC (Normal) | Moderado | Lactose intolerant, second LCT variant confirming lactase non-persistence. |
| CT (Portador) | Impacto baixo | Second LCT marker (partial) - consistent with lactase persistence. Note: a DNA test only detects genetic (primary) lactose intolerance; it cannot rule out acquired (secondary) intolerance from age, gut issues or illness, which can affect anyone. |
| TT (Variante) | Normal | Second LCT marker confirms lactase persistence - genetically you can digest lactose into adulthood. Note: this is a genetic result only; acquired (secondary) lactose intolerance from age, gut issues or illness is not detectable by DNA and can still occur. |
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