Central appetite regulation. Satiety signaling.
| Genótipo | Impacto | O que significa |
|---|---|---|
| TT (Normal) | Normal | Normal satiety signaling |
| TC (Portador) | Impacto baixo | Reduced satiety signalling, fullness cues may be weaker. Prioritise protein and fibre at each meal, eat slowly, and maintain regular meal timing. |
| CC (Variante) | Moderado | C/C genotype, impaired satiety signalling at the melanocortin-4 receptor. Higher dietary fiber (30–40 g/day), generous protein at each meal, and structured meal timing significantly improve fullness perception. |
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