Language
Enzima di fase II che metabolizza le ammine aromatiche e l'isoniazide
Gli acetilatori lenti accumulano tossine; gli acetilatori rapidi le eliminano velocemente
| Genotipo | Impatto | Cosa significa |
|---|---|---|
| GG (Normale) | Normale | Fast acetylator - rapid processing of certain drugs and dietary compounds. Standard precautions with charred meat. |
| GA (Portatore) | Impatto basso | Intermediate acetylator - moderate clearance of heterocyclic amines from well-done/charred meat. Favour gentler cooking and marinate before grilling. |
| AA (Variante) | Moderato | Slow acetylator - slower detox of compounds from charred/processed meat. Avoid burnt/charred meat, prefer low-temperature cooking, marinate meats, and eat cruciferous vegetables. |
| Genotipo | Impatto | Cosa significa |
|---|---|---|
| TT (Normale) | Normale | Fast acetylator |
| TC (Portatore) | Moderato | Intermediate acetylator status, moderate drug and carcinogen metabolism. |
| CC (Variante) | Impatto alto | Slow acetylator, slower metabolism of drugs and dietary carcinogens (e.g. heterocyclic amines from grilled meat). Limit charred meats and favour cruciferous vegetables to support Phase II detoxification. |
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