Language
Mantém a enzima MTR em estado ativo
Regenera a metionina sintase funcional por metilacao redutiva
Afeta a capacidade de reciclar a metionina sintase usando B12
| Genótipo | Impacto | O que significa |
|---|---|---|
| AA (Normal) | Normal | Efficient methionine-synthase recycling - supports B12-dependent methylation. Maintain B12 intake (eggs, fish, meat). |
| AG (Portador) | Impacto baixo | Moderately reduced recycling of B12 in the methylation cycle - slightly higher B12 demand. Ensure regular B12 and folate; consider methylcobalamin if levels are low. |
| GG (Variante) | Moderado | Reduced B12 recycling - higher need for B12 and folate to keep homocysteine in check. Prioritise B12-rich foods or methylcobalamin and monitor B12/homocysteine. |
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