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SHMT1
Serine Hydroxymethyltransferase 1
Ciclo di metilazione Chr. 17 1 SNP analizzati

Informazioni su questo gene

Interconverts serine and glycine with THF. Key for one-carbon metabolism.

Varianti analizzate (SNP)

rs1979277 SHMT1 C1420T Frequenza: 30.0%
Genotipo Impatto Cosa significa
CC (Normale) Normale Normal one-carbon metabolism - folate is distributed efficiently between DNA synthesis and methylation. Maintain folate-rich foods.
CT (Portatore) Impatto basso Slightly altered folate flux. Ensure adequate natural folate (leafy greens, legumes) and B12, especially alongside MTHFR variants.
TT (Variante) Moderato May shift folate use and affect methylation. Prioritise natural folate and B12; methylfolate can help if combined with MTHFR variants.

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