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Principal regulador del ritmo circadiano; influye en el ciclo sueño-vigilia, el metabolismo y la secreción hormonal
Factor de transcripción asociado a BMAL1; componente central del reloj circadiano molecular
| Genotipo | Impacto | Qué significa |
|---|---|---|
| TT (Normal) | Normal | Standard circadian rhythm - earlier chronotype tendency. Keep consistent sleep/wake times and morning daylight. |
| TC (Portador) | Impacto bajo | Intermediate chronotype. Anchor regular sleep hours, get morning light, and avoid late heavy meals and screens. |
| CC (Variante) | Moderado | Evening chronotype tendency - later body clock, higher risk of late eating and short sleep. Favour an earlier eating window, morning light and a consistent schedule. |
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